{"id":805,"date":"2021-09-05T02:55:54","date_gmt":"2021-09-05T02:55:54","guid":{"rendered":"https:\/\/www.lumultra.com\/blog\/?p=805"},"modified":"2021-11-02T06:11:23","modified_gmt":"2021-11-02T06:11:23","slug":"research-identifies-new-drug-targets-to-enhance-memory-what-we-know-so-far","status":"publish","type":"post","link":"https:\/\/www.lumultra.com\/blog\/research-identifies-new-drug-targets-to-enhance-memory-what-we-know-so-far\/","title":{"rendered":"Research Identifies New Drug Targets to Enhance Memory: What We Know So Far"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-830\" src=\"https:\/\/www.lumultra.com\/blog\/wp-content\/uploads\/2021\/09\/pexels-ivan-samkov-4240580-1.jpg\" alt=\"\" width=\"434\" height=\"651\" srcset=\"https:\/\/www.lumultra.com\/blog\/wp-content\/uploads\/2021\/09\/pexels-ivan-samkov-4240580-1.jpg 640w, https:\/\/www.lumultra.com\/blog\/wp-content\/uploads\/2021\/09\/pexels-ivan-samkov-4240580-1-200x300.jpg 200w\" sizes=\"(max-width: 434px) 85vw, 434px\" \/>New findings from a University of Bristol study has identified drug targets within the brain\u2019s neural circuits that encode memories.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This, according to the team, will help advance the treatment of a broad spectrum of brain disorders plaguing modern humans.\u00a0<\/span><\/p>\n<p><b>Study Findings<\/b><\/p>\n<p><span style=\"font-weight: 400;\">In the research <\/span><span style=\"font-weight: 400;\">done<\/span><span style=\"font-weight: 400;\"> in collaboration with a biopharmaceutical company, the findings identified specific brain receptors for the neurotransmitter acetylcholine, rerouting information that flows through memory circuits in the hippocampus of the brain.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Acetylcholine is a familiar name in brain enhancement. It\u2019s released in the brain during the learning process and is important for acquiring new memories. Today the only effective treatment for symptoms of brain diseases such as Alzheimer\u2019s disease is the use of drugs that boost acetylcholine levels. The strategy, however, is prone to multiple adverse side effects, so the researchers hope to discover receptor targets that can offer the benefits without the negative effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many brain disorders that feature memory loss include Alzheimer\u2019s and schizophrenia. Treatment options for these problems are still limited and, as mentioned earlier, offer limited success.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The findings, says lead author and professor Jack Mellor, show the fundamental processes occurring in the brain during memory encoding as well as how they may be regulated by drug therapy or brain state. Discovering these specific targets, he adds, \u201copen up avenues and opportunities for the development of new treatments\u201d targeting Alzheimer\u2019s and similar conditions affecting cognitive abilities.<\/span><\/p>\n<p><b>Acetylcholine in Focus<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Diet is believed to play a role in producing acetylcholine and a reduced risk of certain diseases. Acetylcholine is a neurotransmitter produced in the brain, playing a crucial role in muscle movement, working memory, and thinking. Working memory, for example, is the ability of the brain to temporarily hold information in the mind.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When there are problems with the use and production of acetylcholine, disease may set off, including dementia and an autoimmune disease that weakens the muscles, called myasthenia gravis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">How about acetylcholine receptors? They are proteins to which the neurotransmitter binds, letting signals flow from a nerve cell to another. Drugs are created to work on acetylcholine receptors for a variety of medical purposes, including treating Alzheimer\u2019s disease. These medications are called agonists if they stimulate acetylcholine receptors, and antagonists if they inhibit receptors.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When it comes to food or supplements, there is really none that contains acetylcholine. Some, however, may contain the building blocks of the chemical. Choline, an essential nutrient, is a building block of acetylcholine, and it\u2019s found in foods such as whole eggs, fish, meats, and whole grains.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Animal and human studies suggest that choline-rich foods and supplements may increase levels of acetylcholine in the brain, showing the great potential of choline to protect against the risk of certain brain disorders. The complicated relationship between choline and brain function is still being explored by medical research today.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">High-quality supplementation is considered a potent way to get brain enhancement benefits with little or no side effects when done correctly and prudently. It can promote neuroplasticity, the human brain\u2019s ability to reorganize itself through forming new neural connections in life. The brain can be shaped and sharpened to attain greatness, and the right diet and lifestyle can optimize its performance.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Keep posted for more brain enhancement news, studies, and updates straight from authoritative sources. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>New findings from a University of Bristol study has identified drug targets within the brain\u2019s neural circuits that encode memories.\u00a0 This, according to the team, will help advance the treatment of a broad spectrum of brain disorders plaguing modern humans.\u00a0 Study Findings In the research done in collaboration with a biopharmaceutical company, the findings identified&#8230;<\/p>\n","protected":false},"author":1,"featured_media":830,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - 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